BACKGROUND: Differentiating major depressive disorder (MDD) from bipolar disorder (BD) remains a significant clinical challenge, as both disorders exhibit overlapping symptoms but require distinct treatment approaches. Advances in voxel-based morphom...
BACKGROUND: Menopausal hormone therapy (MHT) is generally thought to be neuroprotective, yet results have been inconsistent. Here, we present a comprehensive study of MHT use and brain characteristics in females from the UK Biobank.
BACKGROUND: Major Depressive Disorder (MDD) is a prevalent mental health condition with significant societal impact. Structural magnetic resonance imaging (sMRI) and machine learning have shown promise in psychiatry, offering insights into brain abno...
Pediatric bipolar disorder (PBD) is a highly debilitating condition, characterized by alternating episodes of mania and depression, with intervening periods of remission. Limited information is available about the functional and structural abnormalit...
OBJECTIVE: Subjective tinnitus often coexists with hearing loss, and they share common pathophysiological mechanisms. This comorbidity induces whole-brain gray matter volume (GMV) alterations, manifesting as distributed structural changes in neural n...
AJNR. American journal of neuroradiology
Apr 2, 2025
BACKGROUND AND PURPOSE: Recent advances in deep learning have shown promising results in medical image analysis and segmentation. However, most brain MRI segmentation models are limited by the size of their data sets and/or the number of structures t...
PURPOSE: Dynamic glucose enhanced (DGE) MRI studies employ CEST or spin lock (CESL) to study glucose uptake. Currently, these methods are hampered by low effect size and sensitivity to motion. To overcome this, we propose to utilize exchange-based li...
The immersive experience provided by our approach empowers researchers with an intuitive exploration of brain structures. Within the brain's central nervous system, encompassing both white and gray matter, symptoms associated with Alzheimer's disease...
BACKGROUND: Infant brain tissue segmentation from MRI data is a critical task in medical imaging, particularly challenging due to the evolving nature of tissue contrasts in the early months of life. The difficulty increases as gray matter (GM) and wh...
OBJECTIVE: Accurate personalized survival prediction in amyotrophic lateral sclerosis is essential for effective patient care planning. This study investigates whether grey and white matter changes measured by magnetic resonance imaging can improve i...
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