Three-dimensional dose prediction for lung IMRT patients with deep neural networks: robust learning from heterogeneous beam configurations.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: The use of neural networks to directly predict three-dimensional dose distributions for automatic planning is becoming popular. However, the existing methods use only patient anatomy as input and assume consistent beam configuration for all patients in the training database. The purpose of this work was to develop a more general model that considers variable beam configurations in addition to patient anatomy to achieve more comprehensive automatic planning with a potentially easier clinical implementation, without the need to train specific models for different beam settings.

Authors

  • Ana María Barragán-Montero
    Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Dan Nguyen
    University of Massachusetts Chan Medical School, Worcester, Massachusetts.
  • Weiguo Lu
    Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX, United States of America.
  • Mu-Han Lin
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Roya Norouzi-Kandalan
    Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Xavier Geets
    Center of Molecular Imaging, Radiotherapy and Oncology (MIRO), UCLouvain, Brussels, Belgium.
  • Edmond Sterpin
    Center of Molecular Imaging, Radiotherapy and Oncology (MIRO), UCLouvain, Brussels, Belgium.
  • Steve Jiang