Multivariate classification of drug-naive obsessive-compulsive disorder patients and healthy controls by applying an SVM to resting-state functional MRI data.

Journal: BMC psychiatry
PMID: 31277632

Abstract

BACKGROUND: Previous resting-state functional magnetic resonance imaging (rs-fMRI) studies have revealed intrinsic regional activity alterations in obsessive-compulsive disorder (OCD), but those results were based on group analyses, which limits their applicability to clinical diagnosis and treatment at the level of the individual.

Authors

  • Xi Yang
    Department of Health Outcomes and Biomedical Informatics.
  • Xinyu Hu
    Huaxi MR Research Center (HMRRC) Department of Radiology, West China Hospital Sichuan University, Chengdu, 610041, China.
  • Wanjie Tang
    Mental Health Center Department of Psychiatry, West China Hospital Sichuan University, Chengdu, China.
  • Bin Li
    Department of Magnetic Resonance Imaging (MRI), Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
  • Yanchun Yang
    Mental Health Center Department of Psychiatry, West China Hospital Sichuan University, Chengdu, China. yanchunyang1958@sina.com.
  • Qiyong Gong
    Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Xiaoqi Huang
    Huaxi MR Research Center (HMRRC) Department of Radiology, West China Hospital Sichuan University, Chengdu, 610041, China. julianahuang@163.com.

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