Joint Prediction of Breast Cancer Histological Grade and Ki-67 Expression Level Based on DCE-MRI and DWI Radiomics.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

OBJECTIVE: Histologic grade and Ki-67 proliferation status are important clinical indictors for breast cancer prognosis and treatment. The purpose of this study is to improve prediction accuracy of these clinical indicators based on tumor radiomic analysis.

Authors

  • Ming Fan
    Institute of Biomedical Engineering and Instrumentation, Hangzhou Dianzi University, Hangzhou 310018, China.
  • Wei Yuan
    1 School of Mechanical Engineering, Tianjin University, Tianjin, China.
  • Wenrui Zhao
  • Maosheng Xu
    Department of Radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China.
  • Shiwei Wang
    PTN Graduate Program, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, PR China.
  • Xin Gao
    Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey, USA.
  • Lihua Li
    College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, Hangzhou 310018, China. Electronic address: lilh@hdu.edu.cn.