Machine learning in the prediction of depression treatment outcomes: a systematic review and meta-analysis.

Journal: Psychological medicine
Published Date: Oct 12, 2021

Abstract

BACKGROUND: Multiple treatments are effective for major depressive disorder (MDD), but the outcomes of each treatment vary broadly among individuals. Accurate prediction of outcomes is needed to help select a treatment that is likely to work for a given person. We aim to examine the performance of machine learning methods in delivering replicable predictions of treatment outcomes.

Authors

  • Mehri Sajjadian
    Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.
  • Raymond W Lam
    Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.
  • Roumen Milev
    Department of Psychiatry and Psychology, Queen's University, Providence Care Hospital, Kingston, ON, Canada.
  • Susan Rotzinger
    Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
  • Benicio N Frey
    Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
  • Claudio N Soares
    Department of Psychiatry, Queen's University School of Medicine, Kingston, ON, Canada.
  • Sagar V Parikh
    Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA.
  • Jane A Foster
    Department of Psychiatry & Behavioural Neurosciences, St. Joseph's Healthcare, Hamilton, ON, Canada.
  • Gustavo Turecki
    Department of Psychiatry, Douglas Institute, McGill University, Montreal, QC, Canada.
  • Daniel J Müller
    Campbell Family Mental Health Research Institute, Center for Addiction and Mental Health, Toronto, ON, Canada.
  • Stephen C Strother
    Baycrest and Department of Medical Biophysics, Rotman Research Center, University of Toronto, Toronto, ON, Canada.
  • Faranak Farzan
    eBrain Lab, School of Mechatronic Systems Engineering, Simon Fraser University, Surrey, BC, Canada.
  • Sidney H Kennedy
    Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
  • Rudolf Uher
    Department of Psychiatry, Dalhousie University, Halifax, NS, Canada.

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