A genome-wide multiphenotypic association analysis identified candidate genes and gene ontology shared by four common risky behaviors.

Journal: Aging
PMID:

Abstract

BACKGROUND: Risky behaviors can lead to huge economic and health losses. However, limited efforts are paid to explore the genetic mechanisms of risky behaviors.

Authors

  • Jing Ye
    d Department of Digestive System Diseases, The First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, Xinjiang Province, China.
  • Li Liu
    Metanotitia Inc., Shenzhen, China.
  • Xiaoqiao Xu
    Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
  • Yan Wen
  • Ping Li
    Department of Gastroenterology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
  • Bolun Cheng
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Shiqiang Cheng
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Lu Zhang
    Department of Computer Science and Engineering, The University of Texas at Arlington, Arlington, TX, United States.
  • Mei Ma
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Xin Qi
  • Chujun Liang
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Om Prakash Kafle
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Cuiyan Wu
    Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, 410081, China.
  • Sen Wang
    Key Laboratory of Animal Production, Product Quality and Security, Ministry of Education, Key Laboratory of Animal Nutrition and Feed Science, Jilin Province, College of Animal Science and Technology, Jilin Agricultural University, Changchun, 130118, China.
  • Xi Wang
    School of Information, Central University of Finance and Economics, Beijing, China.
  • Yujie Ning
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Xiaomeng Chu
    Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
  • Lin Niu
    Clinical Research Center of Shaanxi Province for Dental and Maxillofacial Diseases, College of Stomatology, Xi'an Jiaotong University, Xi'an, China.
  • Feng Zhang
    Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China; Key Laboratory of Food Quality and Safety for State Market Regulation, Beijing 100176, China. Electronic address: fengzhang@126.com.