A deep learning algorithm to detect chronic kidney disease from retinal photographs in community-based populations.

Journal: The Lancet. Digital health
PMID: 33328123

Abstract

BACKGROUND: Screening for chronic kidney disease is a challenge in community and primary care settings, even in high-income countries. We developed an artificial intelligence deep learning algorithm (DLA) to detect chronic kidney disease from retinal images, which could add to existing chronic kidney disease screening strategies.

Authors

  • Charumathi Sabanayagam
    Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.
  • Dejiang Xu
    School of Computing, National University of Singapore, Singapore.
  • Daniel S W Ting
    Singapore National Eye Center, Duke-National University of Singapore Medical School, Singapore 168751, Singapore; National Institutes of Health Research Biomedical Research Centre Biomedical Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK. Electronic address: daniel.ting.s.w@singhealth.com.sg.
  • Simon Nusinovici
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Riswana Banu
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
  • Haslina Hamzah
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Cynthia Lim
    Singapore General Hospital, Singapore.
  • Yih-Chung Tham
    Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore.
  • Carol Y Cheung
    Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong Special Administrative Region, China. Electronic address: carolcheung@cuhk.edu.hk.
  • E Shyong Tai
    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Ya Xing Wang
    Beijing Visual Science and Translational Eye Research Institute (BERI), Eye Center of Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
  • Jost B Jonas
    Department of Ophthalmology, Ruprecht-Karls University of Heidelberg, Heidelberg, Germany.
  • Ching-Yu Cheng
    Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.
  • Mong Li Lee
    School of Computing, National University of Singapore.
  • Wynne Hsu
    School of Computing, National University of Singapore.
  • Tien Y Wong
    Singapore National Eye Center, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.

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