The Use of Random Forests to Identify Brain Regions on Amyloid and FDG PET Associated With MoCA Score.

Journal: Clinical nuclear medicine
Published Date:

Abstract

PURPOSE: The aim of this study was to evaluate random forests (RFs) to identify ROIs on F-florbetapir and F-FDG PET associated with Montreal Cognitive Assessment (MoCA) score.

Authors

  • Katherine Zukotynski
    Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; and zukotynk@mcmaster.ca.
  • Vincent Gaudet
    Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, Ontario, Canada.
  • Phillip H Kuo
    University of Arizona, Tucson, AZ.
  • Sabrina Adamo
    LC Campbell Cognitive Neurology Unit, Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
  • Maged Goubran
    Imaging Research Laboratories, Robarts Research Institute, London, ON, Canada N6A 5K8; Biomedical Engineering Graduate Program, Western University, London, ON, Canada. Electronic address: mgoubran@robarts.ca.
  • Christopher J M Scott
    Sunnybrook Research Institute, Toronto, Ontario.
  • Christian Bocti
    Université de Sherbrooke, Sherbrooke, QC.
  • Michael Borrie
    Division of Geriatric Medicine, University of Western Ontario, London, ON, Canada.
  • Howard Chertkow
    Jewish General Hospital, Montreal, QC.
  • Richard Frayne
    Departments of Radiology and Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada; Calgary Image Processing and Analysis Centre, Foothills Medical Centre, Alberta Health Services, Calgary, Alberta, Canada; Seaman Family Magnetic Resonance Research Centre, Foothills Medical Centre, Alberta Health Services, Calgary, Alberta, Canada.
  • Robin Hsiung
    University of British Columbia, Vancouver, BC.
  • Robert Laforce
    Université Laval, Québec, QC.
  • Michael D Noseworthy
    McMaster Integrative Neuroscience Discovery and Study (MiNDS), McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4K1, Canada; Department of Electrical and Computer Engineering, McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4K1, Canada; McMaster School of Biomedical Engineering, McMaster University, 1280 Main St. W., Hamilton, Ontario L8S 4K1, Canada; Imaging Research Centre, St. Joseph's Healthcare Hamilton, 50 Charlton Ave. E., Hamilton, Ontario L8N 4A6, Canada.
  • Frank S Prato
    Lawson Imaging, Lawson Health Research Institute, 268 Grosvenor St., London, Ontario, N6A 4 V2, Canada.
  • Demetrios J Sahlas
    McMaster University, Hamilton.
  • Eric E Smith
    Hotchkiss Brain Institute, University of Calgary, Calgary, AB.
  • Vesna Sossi
    Department of Physics & Astronomy, University of British Columbia, Vancouver, BC, Canada.
  • Alexander Thiel
    1 McGill University, Montréal, QC, Canada.
  • Jean-Paul Soucy
    Montreal Neurological Institute, Montreal, QC.
  • Jean-Claude Tardif
    Montreal Heart Institute, Université de Montréal, Montreal, QC.
  • Sandra E Black
    Institute of Medical Science, University of Toronto, Toronto, ON Canada.