Machine Learning Methods for Optimal Radiomics-Based Differentiation Between Recurrence and Inflammation: Application to Nasopharyngeal Carcinoma Post-therapy PET/CT Images.

Journal: Molecular imaging and biology
Published Date:

Abstract

PURPOSE: To identify optimal machine learning methods for radiomics-based differentiation of local recurrence versus inflammation from post-treatment nasopharyngeal positron emission tomography/X-ray computed tomography (PET/CT) images.

Authors

  • Dongyang Du
    Department of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
  • Hui Feng
    School of Biomedical Engineering and Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, 510515, Guangdong, China.
  • Wenbing Lv
    Department of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
  • Saeed Ashrafinia
    Department of Electrical & Computer Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA.
  • Qingyu Yuan
    Nanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
  • Quanshi Wang
    Nanfang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, Guangdong, China.
  • Wei Yang
    Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, PR China. Electronic address: 421063202@qq.com.
  • Qianjin Feng
    Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou, China. Electronic address: qianjinfeng08@gmail.com.
  • Wufan Chen
    Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou, China.
  • Arman Rahmim
  • Lijun Lu
    School of Biomedical Engineering, Southern Medical University, Guangzhou, China.