Machine Learning Based Radiomic HPV Phenotyping of Oropharyngeal SCC: A Feasibility Study Using MRI.

Journal: The Laryngoscope
Published Date:

Abstract

OBJECTIVES: To investigate whether a radiomic MRI feature-based prediction model can differentiate oropharyngeal squamous cell carcinoma (SCC) according to the human papillomavirus (HPV) status.

Authors

  • Beomseok Sohn
    Department of Radiology, Research Institute of Radiological Science and Center for Clinical Image Data Science, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, Korea.
  • Yoon Seong Choi
    Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, South Korea.
  • Sung Soo Ahn
    Department of Radiology, Severance Hospital, Research Institute of Radiological Science and Center for Clinical Image Data Science, Yonsei University College of Medicine, Seoul, Korea. sungsoo@yuhs.ac.
  • Hwiyoung Kim
    Department of Radiological Science, Yonsei University College of Medicine, Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. Electronic address: HYKIM82@yuhs.ac.
  • Kyunghwa Han
    From the Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea (S.H.P.); and Department of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, South Korea (K.H.).
  • Seung-Koo Lee
    Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 120-752, South Korea.
  • Jinna Kim
    Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, South Korea.