AIMC Topic: Oropharyngeal Neoplasms
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Deep Learning Model of Primary Tumor and Metastatic Cervical Lymph Nodes From CT for Outcome Predictions in Oropharyngeal Cancer.
JAMA network open
May 1, 2025
IMPORTANCE: Primary tumor (PT) and metastatic cervical lymph node (LN) characteristics are highly associated with oropharyngeal squamous cell carcinoma (OPSCC) prognosis. Currently, there is a lack of studies to combine imaging characteristics of bot...
Use of ChatGPT for patient education involving HPV-associated oropharyngeal cancer.
American journal of otolaryngology
Apr 21, 2025
OBJECTIVE: This study aims to investigate the ability of ChatGPT to generate reliably accurate responses to patient-based queries specifically regarding oropharyngeal squamous cell carcinoma (OPSCC) of the head and neck.
Artificial intelligence-based virtual staining platform for identifying tumor-associated macrophages from hematoxylin and eosin-stained images.
European journal of cancer (Oxford, England : 1990)
Mar 26, 2025
BACKGROUND: Virtual staining is an artificial intelligence-based approach that transforms pathology images between stain types, such as hematoxylin and eosin (H&E) to immunohistochemistry (IHC), providing a tissue-preserving and efficient alternative...
Uncertainty-aware deep learning for segmentation of primary tumor and pathologic lymph nodes in oropharyngeal cancer: Insights from a multi-center cohort.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Mar 25, 2025
PURPOSE: Information on deep learning (DL) tumor segmentation accuracy on a voxel and a structure level is essential for clinical introduction. In a previous study, a DL model was developed for oropharyngeal cancer (OPC) primary tumor (PT) segmentati...
Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.
EBioMedicine
Mar 22, 2025
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...
PET and CT based DenseNet outperforms advanced deep learning models for outcome prediction of oropharyngeal cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Mar 19, 2025
BACKGROUND: In the HECKTOR 2022 challenge set [1], several state-of-the-art (SOTA, achieving best performance) deep learning models were introduced for predicting recurrence-free period (RFP) in head and neck cancer patients using PET and CT images.
Human papillomavirus (HPV) prediction for oropharyngeal cancer based on CT by using off-the-shelf features: A dual-dataset study.
Journal of applied clinical medical physics
Mar 2, 2025
BACKGROUND: This study aims to develop a novel predictive model for determining human papillomavirus (HPV) presence in oropharyngeal cancer using computed tomography (CT). Current image-based HPV prediction methods are hindered by high computational ...
Prognosis of p16 and Human Papillomavirus Discordant Oropharyngeal Cancers and the Exploration of Using Natural Language Processing to Analyze Free-Text Pathology Reports.
JCO clinical cancer informatics
Feb 18, 2025
PURPOSE: Treatment deintensification for human papillomavirus-positive (HPV+)-associated oropharyngeal cancer (OPC) has been the catalyst of experts worldwide. In situ hybridization is optimal to identify HPV+ OPC, but immunohistochemistry for its su...
Artificial intelligence for image recognition in diagnosing oral and oropharyngeal cancer and leukoplakia.
Scientific reports
Jan 29, 2025
Visual diagnosis is one of the key features of squamous cell carcinoma of the oral cavity (OSCC) and oropharynx (OPSCC), both subsets of head and neck squamous cell carcinoma (HNSCC) with a heterogeneous clinical appearance. Advancements in artificia...
Leveraging Deep Learning for Immune Cell Quantification and Prognostic Evaluation in Radiotherapy-Treated Oropharyngeal Squamous Cell Carcinomas.
Laboratory investigation; a journal of technical methods and pathology
Jan 16, 2025
The tumor microenvironment plays a critical role in cancer progression and therapeutic responsiveness, with the tumor immune microenvironment (TIME) being a key modulator. In head and neck squamous cell carcinomas (HNSCCs), immune cell infiltration s...
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