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Squamous Cell Carcinoma of Head and Neck

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Transcriptomics-based exploration of ubiquitination-related biomarkers and potential molecular mechanisms in laryngeal squamous cell carcinoma.

BMC medical genomics
BACKGROUND: One of the most common and prevalent cancers is laryngeal squamous cell carcinoma (LSCC), which poses a great threat to the life and health of the patient. Nonetheless, it has been demonstrated that ubiquitination is crucial for the devel...

A radiomics model combining machine learning and neural networks for high-accuracy prediction of cervical lymph node metastasis on ultrasound of head and neck squamous cell carcinoma.

Oral surgery, oral medicine, oral pathology and oral radiology
OBJECTIVE: This study aimed to develop an ultrasound image-based radiomics model for diagnosing cervical lymph node (LN) metastasis in patients with head and neck squamous cell carcinoma (HNSCC) that shows higher accuracy than previous models.

Democratizing cancer detection: artificial intelligence-enhanced endoscopy could address global disparities in head and neck cancer outcomes.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
INTRODUCTION: This article explores the potential role of artificial intelligence (AI) in enhancing the early detection and diagnosis of head and neck squamous cell carcinoma (HNSCC).

Artificial intelligence-based virtual staining platform for identifying tumor-associated macrophages from hematoxylin and eosin-stained images.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Virtual staining is an artificial intelligence-based approach that transforms pathology images between stain types, such as hematoxylin and eosin (H&E) to immunohistochemistry (IHC), providing a tissue-preserving and efficient alternative...

Deep learning informed multimodal fusion of radiology and pathology to predict outcomes in HPV-associated oropharyngeal squamous cell carcinoma.

EBioMedicine
BACKGROUND: We aim to predict outcomes of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC), a subtype of head and neck cancer characterized with improved clinical outcome and better response to therapy. Pathology an...

Machine learning explainability for survival outcome in head and neck squamous cell carcinoma.

International journal of medical informatics
BACKGROUND: Diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC) induces psychological variables and treatment-related toxicity in patients. The evaluation of outcomes is warranted for effective treatment planning and improved dis...

Analysis of AI foundation model features decodes the histopathologic landscape of HPV-positive head and neck squamous cell carcinomas.

Oral oncology
OBJECTIVES: Human papillomavirus (HPV) influences the pathobiology of Head and Neck Squamous Cell Carcinomas (HSNCCs). While deep learning shows promise in detecting HPV from hematoxylin and eosin (H&E) stained slides, the histologic features utilize...

Identification of a telomere-related gene signature for the prognostic and immune landscape prediction in head and neck squamous cell carcinoma by integrated analysis of machine learning and Mendelian randomization.

Medicine
Telomere-related genes (TRGs) are vital in diverse tumor types. Nevertheless, there is a notable lack of in-depth research concerning their significance in head and neck squamous cell carcinoma (HNSCC). In this context, the present study aims to asse...

Multiparameter MRI-based model integrating radiomics and deep learning for preoperative staging of laryngeal squamous cell carcinoma.

Scientific reports
The accurate preoperative staging of laryngeal squamous cell carcinoma (LSCC) provides valuable guidance for clinical decision-making. The objective of this study was to establish a multiparametric MRI model using radiomics and deep learning (DL) to ...