Correlation among cystatin C, homocysteine and arteriosclerosis indexes in patients with chronic kidney disease.

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
PMID:

Abstract

OBJECTIVES: Chronic kidney disease (CKD) has become an important public health problem in the world. The occurrence of cardiovascular events is the main cause of death in patients with CKD, and arteriosclerosis is an important pathophysiological basis for cardiovascular diseases. Nowadays, brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index (ABI) are clinically important indicators to reflect early atherosclerosis. Cystatin C (Cys C)and homocysteine (Hcy) are related to arteriosclerosis in healthy, hypertensive, and diabetic people, while there are few studies on the correlation among Hcy, CysC and arteriosclerosis in patients with CKD. This study aims to investigate the relationship between Cys C, Hcy and atherosclerosis in patients with CKD.

Authors

  • Tianru Chen
    Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013. 522805277@qq.com.
  • Ying Li
    School of Information Engineering, Chang'an University, Xi'an 710010, China.
  • Jiangang Wang
    Health Management Center, Third Xiangya Hospital, Central South University, Changsha 410013, China. 600410@csu.edu.cn.
  • Jianwen Wang
    Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013. jwwangdoc@163.com.