AIMC Topic: Homocysteine
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A large-scale multicenter study of reference intervals and clinical potential for homocysteine-folate cycle metabolites in Northern Chinese population.
Clinica chimica acta; international journal of clinical chemistry
Mar 27, 2025
OBJECTIVES: The study was conducted to establish the reference intervals of homocysteine-folate cycle metabolites based on the healthy population from multiple centers in northern China, and determine their clinical significance in the diagnosis of r...
Relationships between minerals' intake and blood homocysteine levels based on three machine learning methods: a large cross-sectional study.
Nutrition & diabetes
Jun 1, 2024
BACKGROUND: Blood homocysteine (Hcy) level has become a sensitive indicator in predicting the development of cardiovascular disease. Studies have shown an association between individual mineral intake and blood Hcy levels. The effect of mixed mineral...
Disability in multiple sclerosis is associated with age and inflammatory, metabolic and oxidative/nitrosative stress biomarkers: results of multivariate and machine learning procedures.
Metabolic brain disease
Jul 13, 2019
The aim of this study was to evaluate the immune-inflammatory, metabolic, and nitro-oxidative stress (IM&NO) biomarkers as predictors of disability in multiple sclerosis (MS) patients. A total of 122 patients with MS were included; their disability w...
Investigation into homocysteine [corrected], vitamin E and malondialdehyde as indicators of successful artificial insemination in synchronized buffalo cows (Bubalus bubalis).
Research in veterinary science
Nov 30, 2015
The aim of this study was to describe modifications in plasma homocysteine (Hcy), vitamin E (VitE) and malondialdehyde (MDA) concentrations in the first 56 days after artificial insemination (AI) in buffalo. Thirty-five buffalo cows were divided, ex ...
Machine Learning-Enabled Time-Resolved Nanozyme-Encoded Recognition of Endogenous Mercaptans for Disease Diagnosis.
Analytical chemistry
May 20, 2025
With their important role in regulating intracellular redox balance and maintaining cell homeostasis, endogenous mercaptans are recognized as biomarkers of many diseases in clinical practice, and thus establishing efficient yet simple methods to dist...
Unbiased disentanglement of conformational baths with the help of microwave spectroscopy, quantum chemistry, and artificial intelligence: The puzzling case of homocysteine.
The Journal of chemical physics
Aug 21, 2022
An integrated experimental-computational strategy for the accurate characterization of the conformational landscape of flexible biomolecule building blocks is proposed. This is based on the combination of rotational spectroscopy with quantum-chemical...
Correlation among cystatin C, homocysteine and arteriosclerosis indexes in patients with chronic kidney disease.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Dec 28, 2021
OBJECTIVES: Chronic kidney disease (CKD) has become an important public health problem in the world. The occurrence of cardiovascular events is the main cause of death in patients with CKD, and arteriosclerosis is an important pathophysiological basi...
Considerations for automated machine learning in clinical metabolic profiling: Altered homocysteine plasma concentration associated with metformin exposure.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Jan 1, 2018
With the maturation of metabolomics science and proliferation of biobanks, clinical metabolic profiling is an increasingly opportunistic frontier for advancing translational clinical research. Automated Machine Learning (AutoML) approaches provide ex...
Extracted Anaxagorea luzonensis A. Gray Restored Impairment of Endothelium-Dependent Vasorelaxation Induced by Homocysteine Thiolactone in Rat Aortic Rings.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet
Nov 1, 2015
OBJECTIVE: To investigate the beneficial effects of Anaxagorea luzonensis (AL) extract on homocysteine thiolactone (HTL)-induced impairment of endothelium-dependent relaxation in rat aortic rings. The mechanisms involved in the effects of AL on endot...
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