AIMC Topic: Cystatin C
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Explainable machine learning framework for biomarker discovery by combining biological age and frailty prediction.
Scientific reports
Apr 22, 2025
Biological age (BA) and frailty represent two distinct health measures that offer valuable insights into the aging process. Comparing and analyzing blood-based biomarkers from the machine learning (ML) predictors of BA and frailty helps deepen our un...
A comparison of neural networks and regression-based approaches for estimating kidney function in pediatric chronic kidney disease: Practical predictive epidemiology for clinical management of a progressive disease.
Annals of epidemiology
Apr 8, 2025
PURPOSE: Clinical management of pediatric chronic kidney disease requires estimation of glomerular filtration rate (eGFR). Currently, eGFR is determined by two endogenous markers measured in blood: serum creatine (SCr) and cystatin C (CysC). Machine ...
Machine learning algorithms for diabetic kidney disease risk predictive model of Chinese patients with type 2 diabetes mellitus.
Renal failure
Apr 7, 2025
BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetic mellitus (DM). More sensitive methods for early DKD prediction are urgently needed. This study aimed to set up DKD risk prediction models based on machine lear...
Utilizing machine learning approaches to investigate the relationship between cystatin C and serious complications in esophageal cancer patients after esophagectomy.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Dec 16, 2024
BACKGROUND: The purpose of this study is to investigate the relationship between preoperative cystatin C levels and the risk of serious postoperative complications in esophageal cancer (EC) patients, utilizing advanced machine learning (ML) methodolo...
Comparison between the EKFC-equation and machine learning models to predict Glomerular Filtration Rate.
Scientific reports
Nov 2, 2024
In clinical practice, the glomerular filtration rate (GFR), a measurement of kidney functioning, is normally calculated using equations, such as the European Kidney Function Consortium (EKFC) equation. Despite being the most general equation, EKFC, j...
MASP-2 deficiency does not prevent the progression of diabetic kidney disease in a mouse model of type 1 diabetes.
Scandinavian journal of immunology
Dec 25, 2023
Mannan-binding lectin (MBL) initiates the lectin pathway of complement and has been linked to albuminuria and mortality in diabetes. We hypothesize that MBL-associated serine protease 2 (MASP-2) deficiency will protect against diabetes-induced kidney...
[Evaluation of equations using cystatin C for estimation of the glomerular filtration rate in healthy adult population of canidates for kidney donors.].
Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
Sep 8, 2017
The determination of the glomerular filtration rate (GFR) is critical for the selection of potential kidney donors. Methods of measurement of GFR are impractical and complex, which led to development of equations to estimate GFR. Objective: To evalua...
Correlation of Serum Cystatin C with Glomerular Filtration Rate in Patients Receiving Platinum-Based Chemotherapy.
Analytical cellular pathology (Amsterdam)
Dec 18, 2016
. Serum cystatin C seems to be an accurate marker of glomerular filtration rate (GFR) compared to serum creatinine. The aim of this work was to explore the possibility of using serum cystatin C instead of serum creatinine to early predict renal failu...
Serum cystatin C and neutrophil gelatinase-associated lipocalin in predicting the severity of coronary artery disease in diabetic patients.
Anatolian journal of cardiology
Nov 26, 2015
OBJECTIVE: Cystatin C and neutrophil gelatinase-associated lipocalin (NGAL) are biomarkers of renal functions. We evaluated their roles in predicting the severity of coronary artery disease (CAD).
Correlation among cystatin C, homocysteine and arteriosclerosis indexes in patients with chronic kidney disease.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Dec 28, 2021
OBJECTIVES: Chronic kidney disease (CKD) has become an important public health problem in the world. The occurrence of cardiovascular events is the main cause of death in patients with CKD, and arteriosclerosis is an important pathophysiological basi...
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