Mannan-binding lectin (MBL) initiates the lectin pathway of complement and has been linked to albuminuria and mortality in diabetes. We hypothesize that MBL-associated serine protease 2 (MASP-2) deficiency will protect against diabetes-induced kidney...
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
35232902
OBJECTIVES: Chronic kidney disease (CKD) has become an important public health problem in the world. The occurrence of cardiovascular events is the main cause of death in patients with CKD, and arteriosclerosis is an important pathophysiological basi...
AIM: To examine the frequency and risk factors for the development of diastolic dysfunction (DD) of the left ventricle (LV) of the heart in patients with chronic kidney disease (CKD).
Wei sheng yan jiu = Journal of hygiene research
29903187
OBJECTIVE: To prepare human cystatin C( CysC) recombinant protein and produce monoclonal antibodies with high affinity and specificity. Develop a competitive ELISA detection system to detect of CysC in human serum.
Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)
29890099
The determination of the glomerular filtration rate (GFR) is critical for the selection of potential kidney donors. Methods of measurement of GFR are impractical and complex, which led to development of equations to estimate GFR. Objective: To evalua...
In clinical practice, the glomerular filtration rate (GFR), a measurement of kidney functioning, is normally calculated using equations, such as the European Kidney Function Consortium (EKFC) equation. Despite being the most general equation, EKFC, j...
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
39680175
BACKGROUND: The purpose of this study is to investigate the relationship between preoperative cystatin C levels and the risk of serious postoperative complications in esophageal cancer (EC) patients, utilizing advanced machine learning (ML) methodolo...
Biological age (BA) and frailty represent two distinct health measures that offer valuable insights into the aging process. Comparing and analyzing blood-based biomarkers from the machine learning (ML) predictors of BA and frailty helps deepen our un...
PURPOSE: Clinical management of pediatric chronic kidney disease requires estimation of glomerular filtration rate (eGFR). Currently, eGFR is determined by two endogenous markers measured in blood: serum creatine (SCr) and cystatin C (CysC). Machine ...
BACKGROUND: Diabetic kidney disease (DKD) is a common and serious complication of diabetic mellitus (DM). More sensitive methods for early DKD prediction are urgently needed. This study aimed to set up DKD risk prediction models based on machine lear...