A machine-learning algorithm for neonatal seizure recognition: a multicentre, randomised, controlled trial.

Journal: The Lancet. Child & adolescent health
Published Date:

Abstract

BACKGROUND: Despite the availability of continuous conventional electroencephalography (cEEG), accurate diagnosis of neonatal seizures is challenging in clinical practice. Algorithms for decision support in the recognition of neonatal seizures could improve detection. We aimed to assess the diagnostic accuracy of an automated seizure detection algorithm called Algorithm for Neonatal Seizure Recognition (ANSeR).

Authors

  • Andreea M Pavel
    INFANT Research Centre, University College Cork, Cork, Ireland; Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
  • Janet M Rennie
    Institute for Women's Health, University College London, London, UK.
  • Linda S de Vries
  • Mats Blennow
    Department of Neonatal Medicine, Karolinska University Hospital, Stockholm, Sweden; Division of Paediatrics, Department CLINTEC, Karolinska Institutet, Stockholm, Sweden.
  • Adrienne Foran
    Rotunda Hospital, Dublin, Ireland.
  • Divyen K Shah
    Royal London Hospital, London, UK; London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Ronit M Pressler
    Department of Clinical Neurophysiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
  • Olga Kapellou
    Homerton University Hospital NHS Foundation Trust, London, UK.
  • Eugene M Dempsey
    INFANT Research Centre, University College Cork, Cork, Ireland.
  • Sean R Mathieson
    INFANT Research Centre, University College Cork, Cork, Ireland; Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
  • Elena Pavlidis
    INFANT Research Centre, University College Cork, Cork, Ireland; Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
  • Alexander C van Huffelen
    Clinical Neurophysiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Vicki Livingstone
    INFANT Research Centre, University College Cork, Cork, Ireland; Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
  • Mona C Toet
    Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Lauren C Weeke
    Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
  • Mikael Finder
    Department of Neonatal Medicine, Karolinska University Hospital, Stockholm, Sweden; Division of Paediatrics, Department CLINTEC, Karolinska Institutet, Stockholm, Sweden.
  • Subhabrata Mitra
    Institute for Women's Health, University College London, London, UK.
  • Deirdre M Murray
    INFANT Research Centre, University College Cork, Cork, Ireland; Department of Paediatrics and Child Health, University College Cork, Cork, Ireland.
  • William P Marnane
    Irish Centre for Fetal and Neonatal Translational Research (INFANT), Ireland; Department of Electrical and Electronic Engineering, University College Cork, Ireland.
  • Geraldine B Boylan