Comparison of CBCT-based dose calculation methods in head and neck cancer radiotherapy: from Hounsfield unit to density calibration curve to deep learning.

Journal: Medical physics
Published Date: Aug 11, 2020

Abstract

PURPOSE: Anatomical variations occur during head and neck (H&N) radiotherapy treatment. kV cone-beam computed tomography (CBCT) images can be used for daily dose monitoring to assess dose variations owing to anatomic changes. Deep learning methods (DLMs) have recently been proposed to generate pseudo-CT (pCT) from CBCT to perform dose calculation. This study aims to evaluate the accuracy of a DLM and to compare this method with three existing methods of dose calculation from CBCT in H&N cancer radiotherapy.

Authors

  • Anaïs Barateau
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • Renaud de Crevoisier
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • Axel Largent
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France. Electronic address: axel.largent@hotmail.fr.
  • Eugenia Mylona
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • Nicolas Perichon
    Univ. Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, Rennes, F-35000, France.
  • Joël Castelli
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • Enrique Chajon
    Univ. Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, Rennes, F-35000, France.
  • Oscar Acosta
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • Antoine Simon
  • Jean-Claude Nunes
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.
  • Caroline Lafond
    Univ Rennes, CLCC Eugène Marquis, INSERM, LTSI - UMR 1099, F-35000 Rennes, France.

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