Diagnosis of thyroid neoplasm using support vector machine algorithms based on platelet RNA-seq.

Journal: Endocrine
Published Date: Nov 12, 2020

Abstract

OBJECTIVE: To assess the capacity of support vector machine (SVM) algorithms that are developed based on platelet RNA-seq data in identifying thyroid neoplasm patients and differentiating patients with thyroid adenomas, papillary thyroid cancer and metastasized papillary thyroid cancer.

Authors

  • Yuling Shen
    Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China.
  • Yi Lai
    School of Communications and Information Engineering, Xi'an University of Posts and Telecommunications, Xi'an, China.
  • Dong Xu
    Department of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, USA.
  • Le Xu
    Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China.
  • Lin Song
    Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China.
  • Jiaqing Zhou
    Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China.
  • Chengwen Song
    Fun-med Pharmaceutical Technology (Shanghai) Co., Ltd., RM. A310, 115 Xinjunhuan Road, Minhang District, Shanghai, 201100, China.
  • Jiadong Wang
    Department of Head and Neck Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160 Pujian Road, Pudong District, Shanghai, 200127, China. drjiadongw@aliyun.com.

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