Association of a Serum Protein Signature With Rheumatoid Arthritis Development.

Journal: Arthritis & rheumatology (Hoboken, N.J.)
PMID:

Abstract

OBJECTIVE: The pathophysiologic events that precede the onset of rheumatoid arthritis (RA) remain incompletely understood. This study was undertaken to identify changes in the serum proteome that precede the onset of RA, with the aim of providing new insights into the pathogenic mechanisms that lead to its development.

Authors

  • Liam J O'Neil
    University of Manitoba, Winnipeg, Manitoba, Canada.
  • Victor Spicer
    University of Manitoba, Winnipeg, Manitoba, Canada.
  • Irene Smolik
    University of Manitoba, Winnipeg, Manitoba, Canada.
  • Xiaobo Meng
    University of Manitoba, Winnipeg, Manitoba, Canada.
  • Rishi R Goel
    University of Pennsylvania Perelman School of Medicine, Philadelphia.
  • Vidyanand Anaparti
    University of Manitoba, Winnipeg, Manitoba, Canada.
  • John Wilkins
    Feinberg School of Medicine, Northwestern University, Chicago, IL, U.S.A.
  • Hani S El-Gabalawy
    University of Manitoba, Winnipeg, Manitoba, Canada.