Association of a Serum Protein Signature With Rheumatoid Arthritis Development.
Journal:
Arthritis & rheumatology (Hoboken, N.J.)
PMID:
32770634
Abstract
OBJECTIVE: The pathophysiologic events that precede the onset of rheumatoid arthritis (RA) remain incompletely understood. This study was undertaken to identify changes in the serum proteome that precede the onset of RA, with the aim of providing new insights into the pathogenic mechanisms that lead to its development.
Authors
Keywords
Adolescent
Adult
Aged
Anti-Citrullinated Protein Antibodies
Arthritis, Rheumatoid
Asymptomatic Diseases
Calreticulin
Disease Progression
Female
Ficolins
Humans
Indians, North American
Interleukin-1
Lectins
Longitudinal Studies
Machine Learning
Male
Middle Aged
Proteomics
Rheumatoid Factor
Toll-Like Receptor 2
Tumor Necrosis Factor-alpha
Young Adult