High performance in risk stratification of intraductal papillary mucinous neoplasms by confocal laser endomicroscopy image analysis with convolutional neural networks (with video).

Journal: Gastrointestinal endoscopy
Published Date: Jan 16, 2021

Abstract

BACKGROUND AND AIMS: EUS-guided needle-based confocal laser endomicroscopy (EUS-nCLE) can differentiate high-grade dysplasia/adenocarcinoma (HGD-Ca) in intraductal papillary mucinous neoplasms (IPMNs) but requires manual interpretation. We sought to derive predictive computer-aided diagnosis (CAD) and artificial intelligence (AI) algorithms to facilitate accurate diagnosis and risk stratification of IPMNs.

Authors

  • Jorge D Machicado
    Division of Gastroenterology and Hepatology, Mayo Clinic Health System, Eau Claire, Wisconsin, USA.
  • Wei-Lun Chao
    Department of Computer Science and Engineering, College of Engineering, The Ohio State University, Columbus, Ohio, USA.
  • David E Carlyn
    Department of Computer Science and Engineering, College of Engineering, The Ohio State University, Columbus, Ohio, USA.
  • Tai-Yu Pan
    Department of Computer Science and Engineering, College of Engineering, The Ohio State University, Columbus, Ohio, USA.
  • Sarah Poland
    The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Victoria L Alexander
    The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Tassiana G Maloof
    The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Kelly Dubay
    The Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Olivia Ueltschi
    The Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, Columbus, Ohio, USA.
  • Dana M Middendorf
    The Ohio State University College of Medicine, Columbus, Ohio, USA.
  • Muhammed O Jajeh
    Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio, USA.
  • Aadit B Vishwanath
    Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
  • Kyle Porter
    Norwegian University of Science and Technology, Teknologivegen 22, 2815 Gjøvik, Norway.
  • Phil A Hart
    Division of Gastroenterology, Hepatology, and Nutrition, Division of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Georgios I Papachristou
    Division of Gastroenterology, Hepatology, and Nutrition, Division of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Zobeida Cruz-Monserrate
    Division of Gastroenterology, Hepatology, and Nutrition, Division of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Darwin L Conwell
    Division of Gastroenterology, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
  • Somashekar G Krishna
    Division of Gastroenterology, Hepatology, and Nutrition, Division of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

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