AIMC Topic: Microscopy, Confocal

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Deep learning-based segmentation and density estimation of corneal nerves and dendritic cells from In Vivo confocal microscopy images.

Scientific reports
The purpose of this study was to compare manual assessment of corneal nerve fiber length (CNFL) and dendritic cell (DC) density with an automated assessment method utilizing deep learning segmentation to perform rule-based density estimation. Corneal...

Deep learning-aided optical biopsy achieves whole-chain diagnosis of Correa cascade of gastric cancer: a prospective study.

BMC medicine
BACKGROUND: Biopsies are essential in differentiating benign from malignant lesions in routine gastroscopy. Nevertheless, redundant biopsies increase patients' expenses and pathologists' workload. Probe-based confocal laser endomicroscopy (pCLE) enab...

Extracting regions of lipid droplets from confocal microscopy images utilizing optical properties of oleaginous yeast.

Applied microbiology and biotechnology
Non-invasive methods for observing the morphology of living oleaginous yeast are ideal for optimizing the production of various oils, such as food oils, oleochemicals, and biodiesel, from oleaginous yeast. However, existing methods have been develope...

Comparative performance of deep learning architectures for diabetic peripheral neuropathy detection using corneal confocal microscopy: a retrospective single-centre study.

BMJ open
OBJECTIVES: This study aims to develop a deep learning algorithm (DLA) using the InceptionV3 architecture for effective diabetic peripheral neuropathy (DPN) screening via corneal confocal microscopy (CCM) images.

Characterising corneal changes in aniridia-related keratopathy using in vivo confocal microscopy and a self-supervised AI model.

BMJ open ophthalmology
PURPOSE: To investigate whether corneal changes observed via in vivo confocal microscopy (IVCM) in patients with aniridia-related keratopathy (ARK) reflect clinical severity.

Diagnostic Adjuncts and Biopsy Techniques for Oral Potentially Malignant Disorders and Oral Cavity Squamous Cell Carcinoma.

Dental clinics of North America
Diagnostic adjuncts for oral potentially malignant disorders such as leukoplakia or erythroplakia can aid the clinician in triaging abnormal lesions and facilitate both biopsy site selection and surgical management. No adjuncts replace gold standard ...

Stable distance regression via spatial-frequency state space model for robot-assisted endomicroscopy.

International journal of computer assisted radiology and surgery
PURPOSE: Probe-based confocal laser endomicroscopy (pCLE) is a noninvasive technique that enables the direct visualization of tissue at a microscopic level in real time. One of the main challenges in using pCLE is maintaining the probe within a worki...

Multimodal imaging platform for enhanced tumor resection in neurosurgery: integrating hyperspectral and pCLE technologies.

International journal of computer assisted radiology and surgery
PURPOSE: This work presents a novel multimodal imaging platform that integrates hyperspectral imaging (HSI) and probe-based confocal laser endomicroscopy (pCLE) for improved brain tumor identification during neurosurgery. By combining these two modal...

A lightweight PCT-Net for segmenting neural fibers in low-quality CCM images.

Computers in biology and medicine
In this paper, we propose a lightweight Position Channel Transformer Network (PCT-Net) for segmenting slender neural fibers in low-quality corneal confocal microscopy images with speckle noise and uneven lighting. Three modules including the channel ...

Artificial intelligence to enhance the diagnosis of ocular surface squamous neoplasia.

Scientific reports
To provide an artificial intelligence (AI) method using in vivo confocal microscopy (IVCM) to differentiate ocular surface squamous neoplasia (OSSN) from other lesions and compare the performance of well-known AI-related solutions. A dataset of 2,774...