Calprotectin and Neutrophil Gelatinase-Associated Lipocalin As Biomarkers of Acute Kidney Injury in Acute Coronary Syndrome.

Journal: The American journal of the medical sciences
PMID:

Abstract

BACKGROUND: Acute kidney injury (AKI) is increasingly being seen in patients with acute coronary syndromes (ACS) and it is associated with higher short-term and long-term morbidity and mortality. Therefore, it is of paramount importance to identify those ACS patients at risk for the development of AKI. The objective of this study was to evaluate two different plasma biomarkers calprotectin and neutrophil gelatinase-associated lipocalin (NGAL) in early detecting the development of AKI in ACS patients.

Authors

  • Xiao-Wen Zhen
    Department of Nephrology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Ji'nan, China; Department of Diagnostics, BinZhou Medical University, Yantai, Shandong, China.
  • Nian-Peng Song
    Department of Cardiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.
  • Lian-Huan Ma
    Department of Diagnostics, BinZhou Medical University, Yantai, Shandong, China.
  • Li-Na Ma
    Department of Diagnostics, BinZhou Medical University, Yantai, Shandong, China.
  • Ling Guo
    Department of Nephrology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Ji'nan, China. Electronic address: gulixiji@sdu.edu.cn.
  • Xiang-Dong Yang
    Department of Nephrology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Ji'nan, China.