Accurate identification of acute coronary syndrome (ACS) in the prehospital setting is important for timely treatments that reduce damage to the compromised myocardium. Current machine learning approaches lack sufficient performance to safely rule-in...
BACKGROUND: Patients with acute coronary syndrome (ACS) who undergo percutaneous coronary intervention (PCI) remain at high risk for major adverse cardiovascular events (MACE). Conventional risk scores may not capture dynamic or nonlinear changes in ...
BACKGROUND: Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) is a major contributor to cardiovascular mortality, yet reliable tools for individualized mortality prediction remain limited. Machine learning offers the potential to enhance pr...
Simultaneous detection of metabolites and proteins─two chemically and functionally distinct classes of biomolecules─in complex biofluids remains a significant analytical hurdle, yet is critical for early and accurate disease diagnosis. These difficul...
INTRODUCTION: Most acute coronary syndromes (ACS) originate from coronary plaques that are angiographically mild and not flow limiting. These lesions, often characterised by thin-cap fibroatheroma, large lipid cores and macrophage infiltration, are t...
OBJECTIVES: Most patients presenting with chest pain in the emergency medical services (EMS) setting are suspected of non-ST-elevation acute coronary syndrome (NSTE-ACS). Distinguishing true NSTE-ACS from non-cardiac chest pain based solely on the EC...
Obstructive sleep apnea (OSA) may impact outcomes in acute coronary syndrome (ACS) patients. The Global Registry of Acute Coronary Events (GRACE) score assesses cardiovascular risk post-ACS. This study evaluated whether incorporating the STOP-BANG sc...
Coronary artery disease (CAD) is a leading cause of death globally. Antiplatelet therapy remains crucial in preventing and treating CAD-associated thrombotic complications, but it concurrently amplifies the risk of bleeding. Unfortunately, traditiona...
Annals of the Academy of Medicine, Singapore
Apr 22, 2025
INTRODUCTION: Elevated troponin, while essential for diagnosing myocardial infarction, can also be present in non-myocardial infarction conditions. The myocardial-ischaemic-injury-index (MI3) algorithm is a machine learning algorithm that considers a...
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