Predicting adult neuroscience intensive care unit admission from emergency department triage using a retrospective, tabular-free text machine learning approach.

Journal: Scientific reports
PMID:

Abstract

Early admission to the neurosciences intensive care unit (NSICU) is associated with improved patient outcomes. Natural language processing offers new possibilities for mining free text in electronic health record data. We sought to develop a machine learning model using both tabular and free text data to identify patients requiring NSICU admission shortly after arrival to the emergency department (ED). We conducted a single-center, retrospective cohort study of adult patients at the Mount Sinai Hospital, an academic medical center in New York City. All patients presenting to our institutional ED between January 2014 and December 2018 were included. Structured (tabular) demographic, clinical, bed movement record data, and free text data from triage notes were extracted from our institutional data warehouse. A machine learning model was trained to predict likelihood of NSICU admission at 30 min from arrival to the ED. We identified 412,858 patients presenting to the ED over the study period, of whom 1900 (0.5%) were admitted to the NSICU. The daily median number of ED presentations was 231 (IQR 200-256) and the median time from ED presentation to the decision for NSICU admission was 169 min (IQR 80-324). A model trained only with text data had an area under the receiver-operating curve (AUC) of 0.90 (95% confidence interval (CI) 0.87-0.91). A structured data-only model had an AUC of 0.92 (95% CI 0.91-0.94). A combined model trained on structured and text data had an AUC of 0.93 (95% CI 0.92-0.95). At a false positive rate of 1:100 (99% specificity), the combined model was 58% sensitive for identifying NSICU admission. A machine learning model using structured and free text data can predict NSICU admission soon after ED arrival. This may potentially improve ED and NSICU resource allocation. Further studies should validate our findings.

Authors

  • Eyal Klang
    Division of Data-Driven and Digital Medicine (D3M), Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Benjamin R Kummer
    Department of Neurology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, Box 1137, New York, NY, USA. benjamin.kummer@mountsinai.org.
  • Neha S Dangayach
    Icahn School of Medicine at Mount Sinai, Department of Neurological Surgery, New York, NY, United States of America.
  • Amy Zhong
    Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • M Arash Kia
    Institute for Healthcare Delivery Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Prem Timsina
    Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Ian Cossentino
    Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Anthony B Costa
    Department of Neurological Surgery, Icahn School of Medicine, New York, New York, United States of America.
  • Matthew A Levin
    Department of Anesthesiology, Perioperative, and Pain Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L Levy Pl, New York, NY 10029, USA.
  • Eric K Oermann
    Icahn School of Medicine at Mount Sinai, New York, NY, USA.