Leveraging electronic health records data to predict multiple sclerosis disease activity.

Journal: Annals of clinical and translational neurology
Published Date:

Abstract

OBJECTIVE: No relapse risk prediction tool is currently available to guide treatment selection for multiple sclerosis (MS). Leveraging electronic health record (EHR) data readily available at the point of care, we developed a clinical tool for predicting MS relapse risk.

Authors

  • Yuri Ahuja
    Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Nicole Kim
    Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Liang Liang
    Department of Computer Science, University of Miami, Coral Gables, FL.
  • Tianrun Cai
    Harvard-MIT Center for Regulatory Science, Harvard Medical School, Boston, MA, United States.
  • Kumar Dahal
    Division of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Thany Seyok
    Division of Rheumatology, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Chen Lin
    Faculty of Business and Economics, University of Hong Kong, Hong Kong SAR 999077, China.
  • Sean Finan
    From Research Information Systems and Computing (V.M.C., V.G., S.M.), Partners Healthcare; Boston Children's Hospital Informatics Program (D.D., S.F., G.S.); Harvard Medical School (D.D., S.Y., A.C., M.A.-E.-B., N.A.S., S.M., S.T.W., R.D.); Department of Medicine (S.Y., S.T.W.), Department of Neurosurgery (A.C., M.A.-E.-B., R.D.), Division of Rheumatology, Immunology and Allergy (N.A.S.), and Channing Division of Network Medicine (S.T.W., R.D.), Brigham and Women's Hospital, Boston, MA; Center for Statistical Science (S.Y.), Tsinghua University, Beijing, China; Department of Neurology (S.M.), Massachusetts General Hospital; and Biostatistics (T.C.), Harvard School of Public Health, Boston, MA.
  • Katherine Liao
    Brigham and Women's Hospital, Boston, Massachusetts.
  • Guergana Savovoa
    Clinical Natural Language Processing Program, Boston Children's Hospital, Boston, MA, USA.
  • Tanuja Chitnis
    Partners MS Center, Brigham and Women's Hospital, Brookline, Massachusetts, United States of America.
  • Tianxi Cai
    Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
  • Zongqi Xia
    Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.