Batch enrollment for an artificial intelligence-guided intervention to lower neurologic events in patients with undiagnosed atrial fibrillation: rationale and design of a digital clinical trial.

Journal: American heart journal
PMID:

Abstract

BACKGROUND: Clinical trials are a fundamental tool to evaluate medical interventions but are time-consuming and resource-intensive.

Authors

  • Xiaoxi Yao
    Department of Health Sciences Research, Division of Health Care Policy and Research, Mayo Clinic, Rochester, Minnesota.
  • Zachi I Attia
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Emma M Behnken
    Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, MN.
  • Kelli Walvatne
    Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
  • Rachel E Giblon
    Division of Biomedical Statistics and Informatics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
  • Sijia Liu
    These authors contributed equally to this study and Dr. Li is now working at IBM; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; Department of Computer Science and Engineering, University at Buffalo, Buffalo, NY, USA.
  • Konstantinos C Siontis
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
  • Bernard J Gersh
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA.
  • Jonathan Graff-Radford
    Department of Neurology, Mayo Clinic and Foundation, Rochester, MN, USA.
  • Alejandro A Rabinstein
    Department of Neurology, Mayo Clinic, Rochester, MN, USA.
  • Paul A Friedman
    Department of Cardiovascular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
  • Peter A Noseworthy
    Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.