Development and Validation of a Deep Learning Model to Quantify Interstitial Fibrosis and Tubular Atrophy From Kidney Ultrasonography Images.

Journal: JAMA network open
PMID: 34028548

Abstract

IMPORTANCE: Interstitial fibrosis and tubular atrophy (IFTA) is a strong indicator of decline in kidney function and is measured using histopathological assessment of kidney biopsy core. At present, a noninvasive test to assess IFTA is not available.

Authors

  • Ambarish M Athavale
    Division of Nephrology, Department of Medicine, Cook County Health, Chicago, Illinois.
  • Peter D Hart
    Division of Nephrology, Department of Medicine, Cook County Health, Chicago, Illinois.
  • Mathew Itteera
    Division of Nephrology, Department of Medicine, Cook County Health, Chicago, Illinois.
  • David Cimbaluk
    Department of Pathology, Rush University Medical Center, Chicago, Illinois.
  • Tushar Patel
    Mayo Clinic, Jacksonville, FL USA ; Extracellular RNA Communication Consortium (ERCC), ᅟ, ᅟ
  • Anas Alabkaa
    Department of Pathology, Rush University Medical Center, Chicago, Illinois.
  • Jose Arruda
    Division of Nephrology, University of Illinois at Chicago, Chicago.
  • Ashok Singh
    Division of Nephrology, Department of Medicine, Cook County Health, Chicago, Illinois.
  • Avi Rosenberg
    Department of Pathology, Johns Hopkins University, Baltimore, Maryland.
  • Hemant Kulkarni
    M&H Research, LLC, San Antonio, Texas.

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