Prospective evaluation of clarithromycin in recurrent chronic rhinosinusitis with nasal polyps.

Journal: Brazilian journal of otorhinolaryngology
PMID: 32144032

Abstract

INTRODUCTION: The antiinflammatory effects of macrolides, especially clarithromycin, have been described in patients with chronic rhinosinusitis without polyps and also other chronic inflammatory airway diseases. There is no consensus in the literature regarding the effectiveness of clarithromycin in patients with chronic rhinosinusitis with sinonasal polyposis and the national literature does not report any prospective studies on the efficacy of clarithromycin in chronic rhinosinusitis in our population.

Authors

  • Thiago Freire Pinto Bezerra
    Universidade Federal de Pernambuco (UFPE), Hospital das Clínicas, Departamento de Otorrinolaringologia, Recife, PE, Brazil; Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil. Electronic address: oto@thiagobezerra.com.
  • Rogério Pezato
    Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil; Escola Paulista de Medicina (EPM/Unifesp), São Paulo, SP, Brazil.
  • Pâmella Marletti de Barros
    Universidade Federal de Pernambuco (UFPE), Hospital das Clínicas, Departamento de Otorrinolaringologia, Recife, PE, Brazil.
  • Larissa Leal Coutinho
    Universidade Federal de Pernambuco (UFPE), Hospital das Clínicas, Departamento de Otorrinolaringologia, Recife, PE, Brazil.
  • Leidianny Firmino Costa
    Instituição Materno Infantil de Pernambuco (IMIP), Departamento de Otorrinolaringologia, Recife, PE, Brazil.
  • Fabio Pinna
    Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.
  • Richard Voegels
    Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, SP, Brazil.

Keywords

External Resources

Popular Topics
Recent Journals