In-line monitoring and endpoint determination of percolation process of herbal medicine using ultraviolet spectroscopy combined with convolutional neural network.

Journal: The Journal of pharmacy and pharmacology
PMID: 34379131

Abstract

OBJECTIVES: As a common step in the herbal medicine production process, percolation usually lacks effective process monitoring methods and is often conducted with fixed process parameters. In this study, an in-line ultraviolet (UV) spectroscopy was used for monitoring the Caulis Sinomenii percolation process.

Authors

  • Sheng Zhang
    Department of Critical Care Medicine, Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Taizhou, China.
  • Xu Yan
    Dept of Electrical and Computer Engineering, University of California, Los Angeles, CA, 90024, United States.
  • Hao Fu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P. R. China.
  • Wenlong Li
    Institute of Clinical Pharmacology, Qilu Hospital, Shandong University, Jinan, China.
  • Haibin Qu
    Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P. R. China.

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