Single-Examination Risk Prediction of Severe Retinopathy of Prematurity.

Journal: Pediatrics
PMID: 34814160

Abstract

BACKGROUND AND OBJECTIVES: Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. Screening and treatment reduces this risk, but requires multiple examinations of infants, most of whom will not develop severe disease. Previous work has suggested that artificial intelligence may be able to detect incident severe disease (treatment-requiring retinopathy of prematurity [TR-ROP]) before clinical diagnosis. We aimed to build a risk model that combined artificial intelligence with clinical demographics to reduce the number of examinations without missing cases of TR-ROP.

Authors

  • Aaron S Coyner
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.
  • Jimmy S Chen
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.
  • Praveer Singh
    Department of Radiology, MGH/Harvard Medical School, Charlestown, Massachusetts.
  • Robert L Schelonka
    Department of Neonatology, Oregon Health and Science University, Portland, Oregon.
  • Brian K Jordan
    Department of Neonatology, Oregon Health and Science University, Portland, Oregon.
  • Cindy T McEvoy
    Pediatrics, Oregon Health & Science University, Portland, Oregon.
  • Jamie E Anderson
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.
  • R V Paul Chan
    Ophthalmology, Illinois Eye and Ear Infirmary, Chicago, IL, United States.
  • Kemal Sonmez
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.
  • Deniz Erdogmus
    Department of Electrical and Computer Engineering, Northeastern University, Boston, Massachusetts.
  • Michael F Chiang
    National Eye Institute, National Institutes of Health, Bethesda, Maryland.
  • Jayashree Kalpathy-Cramer
    Department of Radiology, MGH/Harvard Medical School, Charlestown, Massachusetts.
  • J Peter Campbell
    Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon.

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