Deep learning reveals cuproptosis features assist in predict prognosis and guide immunotherapy in lung adenocarcinoma.

Journal: Frontiers in endocrinology
PMID: 36060936

Abstract

BACKGROUND: Cuproptosis is a recently found non-apoptotic cell death type that holds promise as an emerging therapeutic modality in lung adenocarcinoma (LUAD) patients who develop resistance to radiotherapy and chemotherapy. However, the Cuproptosis' role in the onset and progression of LUAD remains unclear.

Authors

  • Gang Li
    The Centre for Cyber Resilience and Trust, Deakin University, Australia.
  • Qingsong Luo
    Department of Thoracic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
  • Xuehai Wang
    Department of Thoracic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
  • Fuchun Zeng
    Department of Thoracic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
  • Gang Feng
    Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Science, Haikou 571010, People's Republic of China; Key Laboratory of Monitoring and Control of Tropical Agricultural and Forest Invasive Alien Pests, Ministry of Agriculture, Haikou 571010, People's Republic of China. Electronic address: feng8513@sina.com.
  • Guowei Che
    Department of Thoracic Surgery, West-China Hospital, Sichuan University, Chengdu, China.

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