Deep Learning-Based Computed Tomography Features in Evaluating Early Screening and Risk Factors for Chronic Obstructive Pulmonary Disease.

Journal: Contrast media & molecular imaging
Published Date:

Abstract

This research aimed to investigate the diagnostic effect of computed tomography (CT) images based on a deep learning double residual convolution neural network (DRCNN) model on chronic obstructive pulmonary disease (COPD) and the related risk factors for COPD. The questionnaire survey was conducted among 980 permanent residents aged ≥ 40 years old. Among them, 84 patients who were diagnosed with COPD and volunteered to participate in the experiment and 25 healthy people were selected as the research subjects, and all of them underwent CT imaging scans. At the same time, an image noise reduction model based on the DRCNN was proposed to process CT images. The results showed that 84 of 980 subjects were diagnosed with COPD, and the overall prevalence of COPD in this epidemiological survey was 8.57%. Multivariate logistic regression model analysis showed that the regression coefficients of COPD with age, family history of COPD, and smoking were 0.557, 0.513, and 0.717, respectively ( < 0.05). The diagnostic sensitivity, specificity, and accuracy of DRCNN-based CT for COPD were greatly superior to those of single CT and the difference was considerable ( < 0.05). In summary, advanced age, family history of COPD, and smoking were independent risk factors for COPD. CT based on the DRCNN model can improve the diagnostic accuracy of simple CT images for COPD and has good performance in the early screening of COPD.

Authors

  • Changhong Zhang
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China.
  • Jianhua Liu
    School of Materials Science and Engineering, Ocean University of China, Qingdao 266100, China.
  • Liang Cao
    Hunan Provincial Key Laboratory of Dong Medicine, Hunan University of Medicine, Huaihua, China.
  • Gaixia Feng
    Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Hebei North University, Zhangjiakou 075000, Hebei, China.
  • Zhihua Zhang
    Department of Plastic and Cosmetic Surgery, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120 Guangdong, P.R. China.
  • Mengmeng Ji
    Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine in St. Louis, St. Louis, MO, United States.
  • Yaping Zhang
    Radiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai, 200080 China.