Effect of Health and Training on Ultrasensitive Cardiac Troponin in Marathon Runners.

Journal: The journal of applied laboratory medicine
PMID: 31639753

Abstract

PURPOSE: Cardiac troponin (cTn) is the gold standard biomarker for assessing cardiac damage. Previous studies have demonstrated increases in plasma cTn because of extreme exercise, including marathon running. We developed an easy-to-use, ultrasensitive assay for cardiac troponin I (cTnI) by combining single-molecule counting (SMC™) technology with dried blood spot (DBS) collection techniques and validated the assay on a cohort of marathon runners by correlating postmarathon cTnI elevations with training or risk variables.

Authors

  • Emily N Bishop
    Department of Research and Development, Singulex, Inc., Alameda, CA.
  • Tam Dang
    Department of Research and Development, Singulex, Inc., Alameda, CA.
  • Heather Morrell
    Department of Research and Development, Singulex, Inc., Alameda, CA.
  • Joel Estis
    Department of Research and Development, Singulex, Inc., Alameda, CA.
  • Jeffrey J Bishop
    Department of Research and Development, Singulex, Inc., Alameda, CA. j.bishop@singulex.com.

Keywords

External Resources

Popular Topics
Recent Journals