Ajudecumin A from Ajuga ovalifolia var. calantha exhibits anti-inflammatory activity in lipopolysaccharide-activated RAW264.7 murine macrophages and animal models of acute inflammation.

Journal: Pharmaceutical biology
PMID:

Abstract

CONTEXT: Ajuga ovalifolia Bur. et Franch. var. calantha (Diels) C. Y. Wu et C. Chen (Labiatae), a traditional Chinese medicine, has been used to treat several inflammatory diseases.

Authors

  • Hai Zhang
    a State Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, Sichuan Province and Ministry of Science and Technology, College of Pharmacy and College of Ethnic Medicine , Chengdu University of Traditional Chinese Medicine , Chengdu , China.
  • Qing-Cuo Ren
    a State Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, Sichuan Province and Ministry of Science and Technology, College of Pharmacy and College of Ethnic Medicine , Chengdu University of Traditional Chinese Medicine , Chengdu , China.
  • Yan Ren
    b Department of Traditional Chinese Medicine, College of Pharmacy , Southwest Minzu University , Chengdu , China.
  • Lin Zhao
    c Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education) , West China Second University Hospital Sichuan University , Chengdu , China.
  • Fan Yang
    School of Electrical Engineering and Automation, Jiangsu Normal University, Xuzhou, China.
  • Yi Zhang
    Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin University, Changchun, China.
  • Wen-Ji Zhao
    d Sichuan Academy of Grassland Sciences , Chengdu , China.
  • Yu-Zhu Tan
    a State Key Laboratory Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, Sichuan Province and Ministry of Science and Technology, College of Pharmacy and College of Ethnic Medicine , Chengdu University of Traditional Chinese Medicine , Chengdu , China.
  • Xiao-Fei Shen
    c Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education) , West China Second University Hospital Sichuan University , Chengdu , China.