Advances in computed tomography-based prognostic methods for intracerebral hemorrhage.

Journal: Neurosurgical review
PMID:

Abstract

Spontaneous intracerebral hemorrhage (ICH) has high morbidity and mortality. Computed tomography (CT) plays an important role in the diagnosis, treatment, and research of cerebrovascular diseases. Non-contrast CT is widely used in the clinical diagnosis of ICH because of its high imaging speed and high sensitivity and specificity in the detection of stroke. Many markers-based CT imaging, quantitative parameters, and artificial intelligence (AI) methods based on CT are increasingly used for the prediction of hematoma expansion (HE), prognosis of ICH, and the evaluation of perihematomal edema (PHE). Therefore, we performed a comprehensive review of studies, focusing on current research evidence related to CT use for the prediction of HE and prognostic. This review discusses recent insights into, outlines current limitations, and puts forward suggestions for the challenges and directions of future research. Although at present the prognosis for ICH is not optimistic, the treatment methods remain controversial. However, identifying imaging markers that can evaluate and predict existing possible existing therapeutic targets could help to provide individualized advice for patients and achieve patient risk stratification, which is a key step in improving treatment outcomes.

Authors

  • Xiaoyu Huang
    Key Laboratory of Organofluorine Chemistry and Laboratory of Polymer Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China. Electronic address: xyhuang@sioc.ac.cn.
  • Dan Wang
    Guangdong Pharmaceutical University Guangzhou Guangdong China.
  • Shenglin Li
    College of Artificial Intelligence, Southwest University, Chongqing 400715, China.
  • Qing Zhou
    Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Junlin Zhou
    Department of Radiology, Lanzhou University Second Hospital, 730030 Lanzhou, Gansu, China.