Deep Learning Methods for Detecting Side Effects of Cancer Chemotherapies Reported in a Remote Monitoring Web Application.

Journal: Studies in health technology and informatics
Published Date:

Abstract

The objective of our work was to develop deep learning methods for extracting and normalizing patient-reported free-text side effects in a cancer chemotherapy side effect remote monitoring web application. The F-measure was 0.79 for the medical concept extraction model and 0.85 for the negation extraction model (Bi-LSTM-CRF). The next step was the normalization. Of the 1040 unique concepts in the dataset, 62, 3% scored 1 (corresponding to a perfect match with an UMLS CUI). These methods need to be improved to allow their integration into home telemonitoring devices for automatic notification of the hospital oncologists.

Authors

  • Marie-Hélène Metzger
    Université Lyon 1, UMR CNRS UCBL 5558, Lyon, France.
  • Ahmath Gadji
    Equipe soins primaires et prévention, INSERM U1018, Villejuif, France.
  • Nada Haj Salah
    Equipe soins primaires et prévention, INSERM U1018, Villejuif, France.
  • Wedji Kane
    Equipe soins primaires et prévention, INSERM U1018, Villejuif, France.
  • François Boue
    Service de médecine interne, Hôpital Antoine-Béclère, Assistance Publique Hôpitaux de Paris, Clamart, France.