Explainable deep learning algorithm for distinguishing incomplete Kawasaki disease by coronary artery lesions on echocardiographic imaging.

Journal: Computer methods and programs in biomedicine
PMID:

Abstract

BACKGROUND AND OBJECTIVE: Incomplete Kawasaki disease (KD) has often been misdiagnosed due to a lack of the clinical manifestations of classic KD. However, it is associated with a markedly higher prevalence of coronary artery lesions. Identifying coronary artery lesions by echocardiography is important for the timely diagnosis of and favorable outcomes in KD. Moreover, similar to KD, coronavirus disease 2019, currently causing a worldwide pandemic, also manifests with fever; therefore, it is crucial at this moment that KD should be distinguished clearly among the febrile diseases in children. In this study, we aimed to validate a deep learning algorithm for classification of KD and other acute febrile diseases.

Authors

  • Haeyun Lee
  • Yongsoon Eun
    Department of Electrical Engineering and Computer Science; The Interdisciplinary Studies of Artificial Intelligence.
  • Jae Youn Hwang
  • Lucy Youngmin Eun
    Division of Pediatric Cardiology, Department of Pediatrics, Yonsei University College of Medicine, Seoul 03722, South Korea. Electronic address: lucyeun@yuhs.ac.