Prognostic features of upstaged pT3a renal tumors with fat invasion after robot-assisted partial nephrectomy: is it time for a new subclassification?

Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Published Date: Nov 26, 2022

Abstract

INTRODUCTION: The clinical management of pT3a pathologic-upstaged renal cell carcinoma (RCC) patients is actually controversial. Aim of this study was i) to assess the impact of pT3a upstaging on oncologic outcomes after robot-assisted partial nephrectomy (RAPN) for cT1-T2 RCC; ii) to explore clinical and surgical predictors of pT3a upstaging; iii) to evaluate the differential impact of perinephric fat invasion (PFI) or sinus fat invasion (SFI) on survival outcomes after RAPN in case of upstaged pT3a RCC.

Authors

  • Fabrizio Di Maida
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy.
  • Riccardo Campi
    Department of Urology, University of Florence, Careggi Hospital, Florence, Italy. Electronic address: riccardo.campi@unifi.it.
  • Antonio Andrea Grosso
    Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
  • Luca Lambertini
    Department of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
  • Anna Cadenar
    Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
  • Sofia Giudici
    Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.
  • Alessio Pecoraro
    Unit of Urological Robotic Surgery and Renal Transplantation, University of Florence, Careggi Hospital, Florence, Italy.
  • Andrea Mari
  • Sergio Serni
    Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.
  • Andrea Minervini
    Department of Urology, Careggi Hospital, University of Florence, Florence, Italy.

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