Automated Detection of the Thoracic Ossification of the Posterior Longitudinal Ligament Using Deep Learning and Plain Radiographs.

Journal: BioMed research international
PMID:

Abstract

Ossification of the ligaments progresses slowly in the initial stages, and most patients are unaware of the disease until obvious myelopathy symptoms appear. Consequently, treatment and clinical outcomes are not satisfactory. This study is aimed at developing an automated system for the detection of the thoracic ossification of the posterior longitudinal ligament (OPLL) using deep learning and plain radiography. We retrospectively reviewed the data of 146 patients with thoracic OPLL and 150 control cases without thoracic OPLL. Plain lateral thoracic radiographs were used for object detection, training, and validation. Thereafter, an object detection system was developed, and its accuracy was calculated. The performance of the proposed system was compared with that of two spine surgeons. The accuracy of the proposed object detection model based on plain lateral thoracic radiographs was 83.4%, whereas the accuracies of spine surgeons 1 and 2 were 80.4% and 77.4%, respectively. Our findings indicate that our automated system, which uses a deep learning-based method based on plain radiographs, can accurately detect thoracic OPLL. This system has the potential to improve the diagnostic accuracy of thoracic OPLL.

Authors

  • Sadayuki Ito
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Hiroaki Nakashima
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Naoki Segi
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Jun Ouchida
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Masahiro Oda
    Graduate School of Informatics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
  • Ippei Yamauchi
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Ryotaro Oishi
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Yuichi Miyairi
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Kensaku Mori
    Graduate School of Informatics, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, 464-8601, Japan.
  • Shiro Imagama
    Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.