Metabolic profile of children with extrahepatic portal vein obstruction undergoing meso-Rex bypass.

Journal: The Journal of surgical research
PMID:

Abstract

BACKGROUND: Extrahepatic portal vein obstruction (EHPVO) in children is often associated with growth restriction, which improves after the restoration of portal venous flow with a meso-Rex bypass, but the physiologic mechanism is unknown. The purpose of this study was to investigate the mechanism of growth delay in children with EHPVO by detailing the metabolic and nutritional profile before and after meso-Rex bypass.

Authors

  • Timothy B Lautz
    Department of Surgery, Ann & Robert H Lurie Children's Hospital of Chicago, Feinberg School of Medicine of Northwestern University, Chicago, Illinois. Electronic address: tlautz@luriechildrens.org.
  • Simon Eaton
    Department of Surgery, Great Ormond Street Hospital and Institute of Child Health, University College London, London, UK.
  • Lisa Keys
    Department of Surgery, Ann & Robert H Lurie Children's Hospital of Chicago, Feinberg School of Medicine of Northwestern University, Chicago, Illinois.
  • Joy Ito
    Department of Surgery, Ann & Robert H Lurie Children's Hospital of Chicago, Feinberg School of Medicine of Northwestern University, Chicago, Illinois.
  • Mario Polo
    Department of Surgery, Great Ormond Street Hospital and Institute of Child Health, University College London, London, UK.
  • Jonathan C K Wells
    Department of Surgery, Great Ormond Street Hospital and Institute of Child Health, University College London, London, UK.
  • Agostino Pierro
    Department of Surgery, Great Ormond Street Hospital and Institute of Child Health, University College London, London, UK.
  • Riccardo A Superina
    Department of Surgery, Ann & Robert H Lurie Children's Hospital of Chicago, Feinberg School of Medicine of Northwestern University, Chicago, Illinois.