Biological phenotyping of cellular metabolism is essential for deciphering health and disease states. The Seahorse XF analyzer enables direct measurement of oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), providing insight ...
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major driver of coronary artery disease (CAD). Prior studies often conflate T2DM- and CAD-specific metabolic alterations, limiting insights into CAD pathogenesis in T2DM. This study aimed to distinguis...
Accurately estimating energy requirements is critical for individuals to maintain a healthy life. Traditional methods may be time-consuming, complex, low in accuracy, and costly, thus creating a need for new approaches. This study explores the applic...
Journal of health, population, and nutrition
Oct 29, 2025
BACKGROUND: Physical activity energy expenditure (PAEE) assessment is important for helping individuals maintain energy balance. This study adopts a technological evolution perspective to systematically examine the historical evolution and current pr...
Energy expenditure (EE) assessment is crucial in both sports science and health management. However, current EE prediction models often overlook individual differences and lack dynamic correlation analysis between multi-modal data and EE. Building up...
BACKGROUND: Ischemic stroke (IS) stands as a principal contributor to high rates of sickness and death. The condition's pathological development is complicated, featuring mechanisms like mitochondrial impairment and the activation of microglial cells...
While many mechanisms have been proposed to drive Alzheimer's disease, particularly the accumulation of amyloid plaques and hyperphosphorylation of tau proteins, emerging evidence suggests that they may be the byproducts of earlier damage rather than...
PURPOSE: Colorectal cancer is a highly aggressive malignancy characterized by complex tumor micro-environments and significant drug resistance. We highlighted the critical role of curcumin in inhibiting tumor growth and migration, inducing cuproptosi...
This study aims to enhance the accuracy and efficiency of energy consumption prediction during exercise training and address the limitations of existing methods in terms of data feature extraction, model complexity, and adaptability to practical appl...
BACKGROUND: Wearable activity monitors are increasingly used to characterize physical behavior. The development and validation of these characterization methods require criterion-labeled data typically collected in a laboratory or simulated free-livi...
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