Deep learning nomogram based on Gd-EOB-DTPA MRI for predicting early recurrence in hepatocellular carcinoma after hepatectomy.

Journal: European radiology
Published Date:

Abstract

OBJECTIVES: The accurate prediction of post-hepatectomy early recurrence in patients with hepatocellular carcinoma (HCC) is crucial for decision-making regarding postoperative adjuvant treatment and monitoring. We aimed to explore the feasibility of deep learning (DL) features derived from gadoxetate disodium (Gd-EOB-DTPA) MRI, qualitative features, and clinical variables for predicting early recurrence.

Authors

  • Meng Yan
    School of Computer Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, 430074, China.
  • Xiao Zhang
    Merck & Co., Inc., Rahway, NJ, USA.
  • Bin Zhang
    Department of Psychiatry, Sleep Medicine Center, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Zhijun Geng
    Department of Medical Imaging, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Yuexiu District, Guangzhou, 510060, People's Republic of China.
  • Chuanmiao Xie
    Department of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.
  • Wei Yang
    Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University), Ministry of Education, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Wenhua Road 103, Shenyang 110016, PR China. Electronic address: 421063202@qq.com.
  • Shuixing Zhang
    Medical Imaging Center, First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, PR China; Institute of Molecular and Functional Imaging, Jinan University, Guangzhou, Guangdong, PR China. Electronic address: shui7515@126.com.
  • Zhendong Qi
    Department of Radiology, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Road, Haizhu District, Guangzhou, 510282, People's Republic of China.
  • Ting Lin
    Department of Nephrology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangdong, 510000, China.
  • Qiying Ke
    Medical Imaging Center, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 16, Airport Road, Baiyun District, Guangzhou, 510405, Guangdong, People's Republic of China.
  • Xinming Li
    College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
  • Shutong Wang
    Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Xianyue Quan
    Department of Radiology, Zhujiang Hospital, Southern Medical University, No. 253, Industrial Road, Haizhu District, Guangzhou, 510282, People's Republic of China. quanxianyue2014@163.com.