Bladder contractility index in posterior urethral valve: A new marker for early prediction of progression to renal failure.
Journal:
Journal of pediatric urology
Published Date:
Nov 22, 2017
Abstract
INTRODUCTION: Posterior urethral valve (PUV) is the most common cause of pediatric end stage renal disease (ESRD), imposing a major health burden on medical community caregivers and adversely affecting the quality of life of patients. Chronic kidney disease (CKD) stage III or estimated GFR of <60 mL/min/1.73 m is known to be associated with more adverse renal, cardiovascular, and clinical outcomes. Thus, it is desirable to identify factors predicting the rapid and early progression of disease. In the present study, baseline characteristics and urodynamic study (UDS) parameters of boys with PUV are correlated with CKD progression to IIIB or more.
Authors
Keywords
Biomarkers
Child
Child, Preschool
Cohort Studies
Databases, Factual
Disease Progression
Female
Follow-Up Studies
Humans
India
Kidney Failure, Chronic
Male
Muscle Contraction
Predictive Value of Tests
Proportional Hazards Models
Renal Insufficiency, Chronic
Retrospective Studies
Risk Assessment
ROC Curve
Time Factors
Urethral Stricture
Urinary Bladder
Urinary Bladder Neck Obstruction
Urodynamics
Vesico-Ureteral Reflux