Non-invasively Discriminating the Pathological Subtypes of Non-small Cell Lung Cancer with Pretreatment F-FDG PET/CT Using Deep Learning.

Journal: Academic radiology
Published Date:

Abstract

RATIONALE AND OBJECTIVES: To develop an end-to-end deep learning (DL) model for non-invasively predicting non-small cell lung cancer (NSCLC) pathological subtypes based on F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) images, and to explore the potential value of DL technology.

Authors

  • Hongyue Zhao
    Department of Nuclear Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
  • Yexin Su
    Department of Nuclear Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
  • Zhehao Lyu
    Department of Nuclear Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.
  • Lin Tian
    The Affiliated Mental Health Center of Jiangnan University, Wuxi Central Rehabilitation Hospital, Wuxi, Jiangsu, China.
  • Peng Xu
    Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
  • Lin Lin
    Central Laboratory, The First Affiliated Hospital of Xiamen University, Xiamen, China, zhibinli33@163.com, liusuhuan@xmu.edu.cn.
  • Wei Han
    Department of Pharmacology, The Key Laboratory of Neural and Vascular Biology, The Key Laboratory of New Drug Pharmacology and Toxicology, Ministry of Education, Collaborative Innovation Center of Hebei Province for Mechanism, Diagnosis and Treatment of Neuropsychiatric Diseases, Hebei Medical University, Shijiazhuang, Hebei, China.
  • Peng Fu
    Department of Nuclear Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China. Electronic address: fupeng0451@163.com.