BACKGROUND: Microsatellite instability (MSI) has emerged as a predictive biomarker for immunotherapy response in various cancers, but its role in non-small cell lung cancer (NSCLC) is not fully understood.
Predicting treatment response is an important problem in real-world applications, where the heterogeneity of the treatment response remains a significant challenge in practice. Unsupervised machine learning methods have been proposed to address this ...
Immunotherapy and chemoimmunotherapy are standard treatments for non-oncogene-addicted advanced non-small cell lung cancer (NSCLC). Currently, a limited number of biomarkers, including programmed death-ligand 1 (PD-L1) expression, microsatellite inst...
BMC medical informatics and decision making
40251623
The automated processing of Electronic Health Records (EHRs) poses a significant challenge due to their unstructured nature, rich in valuable, yet disorganized information. Natural Language Processing (NLP), particularly Named Entity Recognition (NER...
BACKGROUND: Delineating the internal gross tumor volume (IGTV) is crucial for the treatment of non-small cell lung cancer (NSCLC). Deep learning (DL) enables the automation of this process; however, current studies focus mainly on multiple phases of ...
PURPOSE: Recurrences after curative resection in early-stage and locoregionally advanced non-small cell lung cancer (NSCLC) are common, necessitating a nuanced understanding of associated risk factors. This study aimed to establish a natural language...
BACKGROUND: There is no standard practice for intensive care admission after non-small cell lung cancer surgery. In this study, we aimed to determine the need for intensive care admission after non-small cell lung cancer surgery with deep learning mo...
Lung cancer remains one of the leading causes of cancer-related deaths worldwide, with early detection being critical to improving patient outcomes. Recent advancements in deep learning have shown promise in enhancing diagnostic accuracy, particularl...
BACKGROUND: Epidermal growth factor receptor (EGFR) mutations are present in 10-60% of all non-small cell lung cancer (NSCLC) patients and are associated with dismal prognosis. Lung cancer brain metastases (LCBM) are a common complication of lung can...
Radiation pneumonia (RP) is the most common side effect of chest radiotherapy, and can affect patients' quality of life. This study aimed to establish a combined model of radiomics, dosiomics, deep learning (DL) based on simulated location CT and dos...