Deep Learning Versus Neurologists: Functional Outcome Prediction in LVO Stroke Patients Undergoing Mechanical Thrombectomy.

Journal: Stroke
PMID:

Abstract

BACKGROUND: Despite evolving treatments, functional recovery in patients with large vessel occlusion stroke remains variable and outcome prediction challenging. Can we improve estimation of functional outcome with interpretable deep learning models using clinical and magnetic resonance imaging data?

Authors

  • Lisa Herzog
    University of Zurich, Epidemiology, Biostatistics and Prevention Institute (EBPI), Hirschengraben 84, 8001 Zurich, Switzerland; Zurich University of Applied Sciences, Institute of Data Analysis and Process Design (IDP), Rosenstrasse 3, 8400 Winterthur, Switzerland. Electronic address: lisa.herzog@uzh.ch.
  • Lucas Kook
    Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Switzerland (L.H., L.K., B.S.).
  • Janne Hamann
    Department of Neurology (L.H., J.H., C.G., A.R.L., S.W.), University Hospital and University of Zurich, Switzerland.
  • Christoph Globas
    Department of Neurology (L.H., J.H., C.G., A.R.L., S.W.), University Hospital and University of Zurich, Switzerland.
  • Mirjam R Heldner
    Department of Neurology (M.R.H., D.S., K.A., L.P., J.K., U.F., M.A.), Inselspital, University Hospital and University of Bern, Switzerland. Department of Neurology, University Hospital Basel, Switzerland (U.F.).
  • David Seiffge
    Department of Neurology (M.R.H., D.S., K.A., L.P., J.K., U.F., M.A.), Inselspital, University Hospital and University of Bern, Switzerland. Department of Neurology, University Hospital Basel, Switzerland (U.F.).
  • Kateryna Antonenko
    Department of Neurology (M.R.H., D.S., K.A., L.P., J.K., U.F., M.A.), Inselspital, University Hospital and University of Bern, Switzerland. Department of Neurology, University Hospital Basel, Switzerland (U.F.).
  • Tomas Dobrocky
    Department of Diagnostic and Interventional Neuroradiology (T.D., J.G., R.W.), Inselspital, University Hospital and University of Bern, Switzerland. Department of Neurology, University Hospital Basel, Switzerland (U.F.).
  • Leonidas Panos
    Department of Neurology (M.R.H., D.S., K.A., L.P., J.K., U.F., M.A.), Inselspital, University Hospital and University of Bern, Switzerland. Department of Neurology, University Hospital Basel, Switzerland (U.F.).
  • Johannes Kaesmacher
    Institute of Diagnostic and Interventional Neuroradiology, Institute of Diagnostic, Interventional and Pediatric Radiology and Department of Neurology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.
  • Urs Fischer
    Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
  • Jan Gralla
  • Marcel Arnold
    Department of Neurology (M.R.H., D.S., K.A., L.P., J.K., U.F., M.A.), Inselspital, University Hospital and University of Bern, Switzerland. Department of Neurology, University Hospital Basel, Switzerland (U.F.).
  • Roland Wiest
    Institute for Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland.
  • Andreas R Luft
    Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
  • Beate Sick
    Zurich University of Applied Sciences, School of Engineering, Winterthur, Switzerland.
  • Susanne Wegener
    University Hospital Zurich, Department of Neurology, Frauenklinikstrasse 26, 8091 Zurich, Switzerland.