The tumor immune microenvironment in pancreatic cancer and its potential in the identification of immunotherapy biomarkers.

Journal: Expert review of molecular diagnostics
Published Date: Dec 15, 2023

Abstract

INTRODUCTION: Pancreatic cancer (PC) has an extremely poor prognosis, even with surgical resection and triplet chemotherapy treatment. Cancer immunotherapy has been recently approved for tumor-agnostic treatment with genome analysis, including in PC. However, it has limited efficacy.

Authors

  • Ryouichi Tsunedomi
    Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
  • Yoshitaro Shindo
    Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
  • Masao Nakajima
    Department of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
  • Kiyoshi Yoshimura
    Division of Medical Oncology, Department of Medicine, Showa University School of Medicine, Shinagawa, Tokyo, Japan.
  • Hiroaki Nagano

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