Mechanism of liver X receptor α and ATP binding cassette transporter A1 involved in preeclampsia using an optimized deep learning model.

Journal: European review for medical and pharmacological sciences

PMID: 37458649

Abstract

OBJECTIVE: Preeclampsia (PE) is a complex disease-causing multisystem damage. Many genes, environmental factors, and their interactions are involved in the development and progression of PE. The pathogenesis of PE is not fully understood, limiting the prevention and treatment of PE. The aim of this study was to investigate the effect of 4,4'-diisothiocyanato-stilbene-2,2'-disulfonic acid (DIDS), an ATP-binding cassette transporter A1 (ABCA1) blocker, on apoM mRNA and protein levels.

Authors

C-C Wu

Department of Obstetrics and Gynecology, Quanzhou First Hospital Affiliated to Fujian Medical University, Quanzhou, China. llc123@fjmu.edu.cn.
D-F Gan
R Cao
L-C Li

Keywords

ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters Cholesterol, HDL Deep Learning Female Humans Liver X Receptors Orphan Nuclear Receptors Pre-Eclampsia RNA, Messenger

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View on PubMed Access via DOI PubMed (37458649)

Mechanism of liver X receptor α and ATP binding cassette transporter A1 involved in preeclampsia using an optimized deep learning model.

Abstract

Authors

Keywords

External Resources

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