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ATP-Binding Cassette Transporters

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Changes in the expression of four ABC transporter genes in response to imidacloprid in Bemisia tabaci Q (Hemiptera: Aleyrodidae).

Pesticide biochemistry and physiology 30744887
Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae), a globally invasive species complex that causes serious damage to field crops, has developed resistance to imidacloprid and many other pesticides. Insect detoxify to pesticides may partially depend...
Abdomen Animals ATP-Binding Cassette Transporters Female Gene Expression Regulation Head Hemiptera Insect Proteins Insecticides Male Neonicotinoids Nitro Compounds Thorax
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Association of ATP-Binding Cassette Transporter (ABC) Gene Polymorphisms with Viral Load in Patients with Genotype 1 Hepatitis C Virus Infection.

Clinical laboratory 28164591
BACKGROUND: ATP-binding cassette transporters (ABC) gene polymorphisms are associated with various biological functions, including hepatitis C virus (HCV) infection. This study aims to explore the impact of ABC transporters polymorphisms on HCV viral...
ATP Binding Cassette Transporter 1 ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1 ATP Binding Cassette Transporter, Subfamily B, Member 11 ATP Binding Cassette Transporter, Subfamily G, Member 2 ATP Binding Cassette Transporter, Subfamily G, Member 5 ATP-Binding Cassette Transporters Female Gene Frequency Genotype Hepacivirus Hepatitis C, Chronic Humans Interleukins Lipoproteins Male Middle Aged Neoplasm Proteins Polymorphism, Single Nucleotide Viral Load
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Classification of Breast Cancer Resistant Protein (BCRP) Inhibitors and Non-Inhibitors Using Machine Learning Approaches.

Combinatorial chemistry & high throughput screening 26004050
The breast cancer resistant protein (BCRP) is an important transporter and its inhibitors play an important role in cancer treatment by improving the oral bioavailability as well as blood brain barrier (BBB) permeability of anticancer drugs. In this ...
ATP Binding Cassette Transporter, Subfamily G, Member 2 ATP-Binding Cassette Transporters Humans Machine Learning Neoplasm Proteins Neural Networks, Computer
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Prediction of causative genes in inherited retinal disorder from fundus photography and autofluorescence imaging using deep learning techniques.

The British journal of ophthalmology 33879469
BACKGROUND/AIMS: To investigate the utility of a data-driven deep learning approach in patients with inherited retinal disorder (IRD) and to predict the causative genes based on fundus photography and fundus autofluorescence (FAF) imaging.
Adolescent Adult Aged Aged, 80 and over Algorithms ATP-Binding Cassette Transporters Child Deep Learning Eye Proteins Female Fluorescein Angiography Follow-Up Studies Fundus Oculi Humans Male Middle Aged Prognosis Retinal Diseases Retrospective Studies Rod Cell Outer Segment Young Adult
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Benchmarking deep learning splice prediction tools using functional splice assays.

Human mutation 33942434
Hereditary disorders are frequently caused by genetic variants that affect pre-messenger RNA splicing. Though genetic variants in the canonical splice motifs are almost always disrupting splicing, the pathogenicity of variants in the noncanonical spl...
ATP-Binding Cassette Transporters Benchmarking Deep Learning Humans Introns Mutation RNA Splice Sites RNA Splicing
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Mechanism of liver X receptor α and ATP binding cassette transporter A1 involved in preeclampsia using an optimized deep learning model.

European review for medical and pharmacological sciences 37458649
OBJECTIVE: Preeclampsia (PE) is a complex disease-causing multisystem damage. Many genes, environmental factors, and their interactions are involved in the development and progression of PE. The pathogenesis of PE is not fully understood, limiting th...
ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters Cholesterol, HDL Deep Learning Female Humans Liver X Receptors Orphan Nuclear Receptors Pre-Eclampsia RNA, Messenger
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Utilizing Machine Learning to Identify Biomarkers of Endoplasmic Reticulum Stress and Analyze Immune Cell Infiltration in Parkinson's Disease.

Molecular neurobiology 38521829
The neurodegenerative disorder known as Parkinson's disease (PD) affects many people. The objective of this investigation was to examine the relationship between immune system infiltration, ATP-binding cassette transporter subfamily A member 7 (ABCA7...
ATP-Binding Cassette Transporters Biomarkers Endoplasmic Reticulum Stress Humans Machine Learning Parkinson Disease
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Combined bioinformatics and machine learning methodologies reveal prognosis-related ceRNA network and propose ABCA8, CAT, and CXCL12 as independent protective factors against osteosarcoma.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University 38315381
BACKGROUND: Aberrant circular RNA (circRNA) acts as an oncogene or suppressor during neoplasm initiation and development. However, the functions of most circRNAs in osteosarcoma (OS) remain unclear.
ATP-Binding Cassette Transporters Biomarkers, Tumor Bone Neoplasms Chemokine CXCL12 Computational Biology Gene Expression Regulation, Neoplastic Gene Regulatory Networks Humans Machine Learning MicroRNAs Osteosarcoma Prognosis Protective Factors RNA, Circular RNA, Competitive Endogenous RNA, Messenger
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