BACKGROUND: Preeclampsia is a severe hypertensive disorder with rising global prevalence. While machine learning (ML) models for predicting preeclampsia are increasingly published, existing evidence shows high heterogeneity, and the distinction betwe...
OBJECTIVES: It remains debated whether gestational hypertension (GH) and pre-eclampsia (PE) are distinct entities or different spectra of the same disease. Currently, comparative studies of risk factors for GH and PE in the same population are limite...
Preeclampsia, characterized by high blood pressure, proteinuria and organ dysfunction in severe cases is a hypertensive disorder that occurs during pregnancy. There is strong evidence that this disease, whose etiology remains unclear, is a complex co...
BACKGROUND: Preeclampsia (PE) is a multisystem disorder characterized primarily by hypertension and proteinuria after 20 weeks of gestation, significantly impacting maternal and fetal health. The etiology remains unclear, but it is primarily attribut...
BACKGROUND: Preeclampsia (PE) is a serious hypertensive complication during pregnancy characterized by immune dysregulation and vascular dysfunction, however, the precise molecular mechanisms and effective therapeutic strategies remain unclear. This ...
Preeclampsia (PE), a devastating pregnancy complication affecting 5% of gravidas worldwide, exhibits poorly characterized connections between mitochondrial dysfunction and immune dysregulation. This study aims to identify integrated mitochondrial-imm...
BACKGROUND: Abnormal hedgehog (Hh) signaling is linked to preeclampsia (PE). This study aimed to identify Hh-related diagnostic biomarkers for PE and assess the role of immune infiltration.
Preeclampsia (PE) and fetal growth restriction (FGR) complicate 5-10% of pregnancies and are major causes of maternal and fetal morbidity and mortality. Here we demonstrate that measuring circulating cell-free RNAs (cfRNAs) from maternal plasma can a...
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Jul 1, 2025
OBJECTIVE: Preeclampsia (PE) is a multifactorial systemic pregnancy disease, in which iron metabolism and ferroptosis play significant roles during its pathogenesis. The diagnosis and prevention of PE remain urgent clinical issues that need to be add...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.